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Conference Full Name: 3rd Edition of International Vaccines Congress
Conference Short Name: IVC 2023
Conference Theme: SAVED: Spearheading Advancements in Vaccine Evolution and Development
Conference Venue: Boston, Massachusetts, USA
Conference Address: Hilton Boston/Woburn,2 Forbes Road, Woburn, Massachusetts, 01801, USA
Event Mode: Hybrid Event: both onsite and online versions
Reach us at:
Contact Email: vccinesa@magnusconference.com
Phone: 1 (702) 988-2320
WhatsApp: +1 (779) 429-2143
Dates: October 23-25, 2023
Venue: Boston, Massachusetts, USA
Website: https://vaccinescongress.com/
Abstract submission: https://vaccinescongress.com/submit-abstract
Registration: https://vaccinescongress.com/register https://vaccinescongress.com/ |
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QDs for gene delivery QDs have been investigated as potential gene carriers due to their chemical stability and large surface area. More importantly, QDs have excellent optical properties, including size-tunable fluorescence peaks, high resistance to photobleaching, and a broad excitation profile with narrow emission spectra. Due to these advantages, the use of QDs for non-viral gene delivery enables monitoring gene delivery in real-time as it happens.
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Fig. 1 Schematic illustration of preparation steps of the Mn:ZnSe QD-based siRNA carriers.
Fig. 1 Schematic illustration of preparation steps of the Mn:ZnSe QD-based siRNA carriers. (Zhao M X, et al., 2016)
QD-based Gene Delivery System Development Services
Our researchers help customers synthesize a series of QDs with small size, low toxicity, positive charge, and strong optical emission characteristics, allowing the QDs to be potential carriers for gene delivery in vitro and in vivo and as fluorescent probes for tracking the delivery of genes into nuclei. We also provide a variety of characterization services to prove that the QD-based nano-carriers produced have good biocompatibility, new gene loading ability, weak acid-induced gene release, and fluorescence imaging tracking, and are suitable for gene delivery. Our services include, but are not limited to:
Synthesis of QDs
We provide a variety of methods such as hot colloid synthesis to help our customers synthesize many high-quality QDs, including many types of core/shell QDs such as CdSe/ZnSe QDs, CdSe/CdS/ZnS, CdTe/CdSe and InP/ZnS. We also offer a top-down approach involving the cutting of larger materials from graphene into GQDs to help our customers synthesize GQDs.
Modification of QDs
We offer a variety of modification strategies to manipulate the surface of QDs and help our customers synthesize QDs-based vectors for efficient gene delivery. For example, the preparation of CdSe aqueous QDs electrostatically coated with polyethyleneimine and pseudohomogeneous nanocarriers based on carbon QDs decorated with arginine.
Characterization of QDs
We offer a wide range of techniques such as Fourier-transform infrared spectroscopy (FT-IR), Atomic force microscopy (AFM), Energy dispersive X-ray (EDX) mapping, and field emission scanning electron microscopy (FE-SEM) to provide our customers with a comprehensive characterization of QDs.
DNA loading test
We provide the zeta-potential test and the agarose gel electrophoresis analysis for the rapid characterization of gene loading of QDs-based vectors for gene delivery.
Cell viability test
We provide an evaluation of the cytotoxicity of nonviral nanocomposite vectors using the MTT assay.
Transfection assay
We provide cellular bioimaging, transfection assay, and fluorimetric assay to investigate the transfection efficiency of QD-based nanocarrier and genetic material complex.
Our company has extensive knowledge and experience in developing non-viral targeting vectors for the efficient delivery of genetic material to cells. We provide our customers with expert scientific services and technical support for the design and manufacture of QD-based nanocarriers. If you are interested in our services, please contact us for more details and a quotation.
Reference
Zhao, M. X.; Zhu, B. J. The research and applications of quantum dots as nano-carriers for targeted drug delivery and cancer therapy. Nanoscale Research Letters, 2016, 11(1): 1-9.
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